Paulo Cilas M. Lyra Jr., PhD

Huang H, Hu C, Na J, Hart SN, Gnanaolivu RD, Abozaid M, Rao T, Tecleab YA; CARRIERS Consortium; Pesaran T, Lyra PCM, Karam R, Yadav S, Nathanson KL, Domchek SM, de la Hoya M, Robson M, Mehine M, Bandlamudi C, Mandelker D, Monteiro ANA, Iversen ES, Boddicker N, Chen W, Richardson ME, Couch FJ. Functional evaluation and clinical classification of BRCA2 variants. Nature. 2025 Jan. DOI: 10.1038/s41586-024-08388-8.

Lyra-Jr PC, Nepomuceno TC, de Souza MLM, Machado GF, Veloso MF, Henriques TB, dos Santos DZ, Ribeiro IG, Ribeiro-Jr RSR, Rangel LBA, Richardson M, Iversen ES, Goldgar D, Couch FJ, Carvalho MA, Monteiro ANA. Integration of functional assay data results provides strong evidence for classification of hundreds of BRCA1 variants of uncertain significance. Genet Med. 2020 Oct.

Gusev A, Lawrenson K, Lin X, Lyra-Jr PC, Kar S, Vavra KC, Segato F, Fonseca MAS, Lee JM, Pejovic T, Liu G, Ovarian Cancer Association Consortium, Karlan BY, Freedman ML, Noushmehr H, Monteiro ANA, Pharoah PDP, Pasaniuc B, Gayther SA. A transcriptome-wide association study of high grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants. Nat Genet. 2019 May. DOI: 10.1038/s41588-019-0395-x.